SCIENTIFIC PUBLICATIONS

Our team drives scientific understanding through peer-reviewed publications and in-depth technical analyses. The following are highlighted articles followed by a comprehensive list of publications authored by our team members, showcasing their expertise and contributions to the field:

Assessing systemic absorption and estrogenic potential of methylparaben and propylparaben in consumer use

Jones, K., M.J. Kemp, and C.A. Barlow
2026. Toxicol Ind Health

Article Link
Cellular defense mechanisms against asbestos fibers

Barlow, C.A. and B.T. Mossman.
2025. Front Public Health 13

Article Link
Evaluating health impacts of exposure to PFAS mixtures: a systematic review of epidemiological studies using mixture methods

Kemp, M.J., K. Thoppe, K. Jones, M. Maltby, K. Ball, and C.A. Barlow.
2025. Crit Rev Toxicol 55(8): 777-795.

Article Link
Asbestos fiber length and its relation to disease risk

Barlow, C.A., M. Grespin, and E.A. Best.
2017 Inhal Toxicol 29(12-14): 541-554

Article Link
Conditional BCL-2 Expression in Fibroblasts Promotes Persistent Pulmonary Fibrosis which is Reversible by Therapeutic BCL-2 Inhibition.

Elizabeth F. Redente, Tengyao Song, Nomin Javkhlan, Benjamin L. Edelman, Daniel G. Foster, Jasmine A. Wilson, Sangeeta Chakraborty, Joseph C. Cooley, Rohit Gaurav, Satria Saguthi, Max A. Seibold, Rachel Z. Blumhagen, David A. Schwartz, Ivana V. Yang, Jennifer Matsuda, James P. Bridges, Rachel L. Zemans, Rubin M. Tuder & David W. H. Riches
2026. Nat Commun 17, 3317.

Article Link

Foster DG, Javkhlan N, Black BP, Vestal BE, Riches DW, Redente EF.
2026. JCI Insight. May 5:e199660.
doi: 10.1172/jci.insight.199660.
Potter, A.M., L.H. Burton, K.S. Santangelo, T.M. Nordgren, and K.J. Sikes.
2026. Arthritis Res Ther 28(1): 67.
doi: 10.1186/s13075-026-03757-2.
Jones, K., M.J. Kemp, and C.A. Barlow
2026. Toxicol Ind Health
https://journals.sagepub.com/doi/10.1177/07482337261419181
Lee, S.H., R. Lu, A. House, Z. Li, L.H. Burton, K.J. Sikes, L.M. Pezzanite, D.W. Koch, K.M. Labus, B. Gadomski, J. Easley, R.T. Tran, and S.C. Heo.
2025. Adv Funct Mater 35(47): 2506063.
doi: 10.1002/adfm.202506063
Van Zeeland, E.M., B. Kassel, T. Montoya, A.J. Saviola, L.H. Burton, J.T. Easley, B.B. Nelson, K.S. Santangelo, and K.J. Sikes.
2025. Osteoarthritis Cartilage 33(8): 992-1006.
doi: 10.1016/j.joca.2025.05.004.
Schmitz, C., C. Alt, T. Wuerfel, S. Milz, J. Dinzey, A. Hill, K.J. Sikes, L.H. Burton, J. Easley, H.L. Stewart, C.M. Puttlitz, B.C. Gadomski, K.M. Labus, D.A. Pearce, N. Maffulli, and E.U. Alt.
2025. Int J Mol Sci 26(14): 6800.
doi: 10.3390/ijms26146800.
Barlow, C.A. and B.T. Mossman.
2025. Front Public Health 13
https://doi.org/10.3389/fpubh.2025.1566473
Sierra A.M.G., L.A. Urbina Moreno, C. Flanigan,J. Jimeno, and D.C. Rivera-Pinzon
2025. Translational and Clinical Pharmacology. 33(3):135-144.
10.12793/tcp.2025.33.e11
Bakour, C., J. Andreadakis, C. Flanigan, S.Muftah, T. Warren, W. M. Rote, S. W. Song, and J. D. Martin.
2025. Digital media use and mental health in adolescents. Annals of Epidemiology. 109:192.
https://doi-org.ezproxy2.library.colostate.edu/10.1016/j.annepidem.2025.07.062
Kemp, M.J., K. Thoppe, K. Jones, M. Maltby, K. Ball, and C.A. Barlow.
2025. Crit Rev Toxicol 55(8): 777-795.
10.1080/10408444.2025.2546427‍ ‍
Bonilla, A.F., K.J. Sikes, L.H. Burton, L. Chow, J. Kurihara, K. Santangelo, S.W. Dow, and J.T. Easley.
2025. Front Vet Sci 11:1382652.
doi: 10.3389/fvets.2024.1382652.
Afzali, M.F., M.M. Sykes, L.H. Burton, K.M. Patton, K.R. Lee, C. Seebart, N. Vigon, R. Ek, G.E. Narez, A.J. Marolf, K.J. Sikes, T.L. Haut Donahue, and K.S. Santangelo.
2024. Ann Transl Med 12(3):43.
doi: 10.21037/atm-23-1886.
Cooley J.C., N. Javkhlan , J.A. Wilson, D.G Foster, B.L. Edelman, L.A. Ortiz, D.A. Schwartz, D.W.H. Riches, and E.F. Redente .
2023. JCI Insight 8 (3): e163762.
10.1172/jci.insight.163762‍ ‍
Radakovich, L.B. and L.H. Burton, L.A. Culver, M.F. Afzali, A.J. Marolf, C.S. Olver, and K.S. Santangelo.
2022. Osteoarthritis Cartilage 30(11): 1482-1494.
doi: 10.1016/j.joca.2022.08.007.
Burton, L.H., M.F. Afzali, L.B. Radakovich, M.A. Campbell, L.A. Culver, C.S. Olver, and K.S. Santangelo.
2022. Free Radic Biol Med 179: 47-58.
doi: 10.1016/j.freeradbiomed.2021.12.257
Ahangari, F., C. Becker, D.G. Foster, M. Chioccioli, M. Nelson, K. Beke, X. Wang, B. Readhead, C. Meador, K. Correll, L.N. Lilli, H.M. Roybal, K.-A. Rose, S. Ding, T. Barnthaler, N. Briones, G. Deluliis, J.C. Schupp, Q. Li, N. Omote, Y. Aschner, K. W. Kopf, B. Magnusson, R. Hicks, A. Backmark, L.P. Cousens, J.T. Dudley, N. Kaminski, and G.P. Downey.
2022. Am J Respir Crit Care Med 206(12): 1463-1479.
10.1164/rccm.202010-3832OC
Spittler, A.P., M.F. Afzali, S.B. Bork, L.H. Burton, L.B. Radakovich, C.A. Seebart, R.A. Moore, and K.S. Santangelo.
2021. PLoS One 16(7): e0253794.
doi: 10.1371/journal.pone.0253794.
Karthigeyan, K. P., C. Flanigan, D. J. Machado, A. A. Kiziltas, D. A Janies, J. Chen, D. Cooke, M. V. Lee, L. J. Saif, S. Henegar, J. Jahnes, D. F. Mielewskim, and J. J. Kwiek.
2021 bioRxiv Preprint.
https://doi.org/10.1101/2021.09.08.459486
Kwiek J. J., C.R. Pickett, C.A. Flanigan, M.V. Lee, L.J. Saif, J. Jahnes, and G. Blonder.
2021 bioRxiv Preprint.
https://doi.org/10.1101/2020.11.12.380196
Gloekler, L.E., C.A. Barlow, B.E. Tvermoes, M.J. La Guardia, and J. Sahmel.
2021. Hum Ecol Risk Assess 27 (9-10): 2288-2310.
https://doi.org/10.1080/10807039.2021.1989662‍ ‍
Aschner, Y., K.A. Correll, D.G. Foster, K.M. Beke, H. Roybal, K.W. Kopf, P.R. Reynolds, C.M. Moore, M.J. Strand, E.L. Burnham, and G. P. Downey.
2021. Am J Respir Crit Care Med. 203: A4373.
10.1152/ajplung.00436.2021‍ ‍
Schweitzer, K.S., T. Crue, J.M. Nall, D. Foster, S. Sajuthi, K.A. Correll, M. Nakamura, J. Everman, G.P. Downey, M.A. Seibold, J.P. Bridges, K.A. Serban, H.W. Chu, and I. Petrache.
2021. Eur Respir J 58(1): 2003988.
‍10.1183/13993003.03988-2020
Kern, J.A., J. Kim, D.G. Foster, R. Mishra, E.E. Gardner, J.T. Poirier, C. Rivard, H. Yu, J.J.H. Finigan, A. Dowlati, C.M. Rudin, and A.C. Tan. 2020.
2021 J Thorac Oncol 15(9): 1522-1534
10.1016/j.jtho.2020.05.026‍ ‍
Burton, L.H. and Radakovich, L.B., A.J. Marolf, and K.S. Santangelo.
2020. Osteoarthritis Cartilage 28(9): 1265-1275.
doi: 10.1016/j.joca.2020.06.005.
Bamber, A., S. Hasanali, A. Nair, S. Watkins, D. Vigil, M. VanDyke, T. McMullin, and K. Richardson.
2019 Int. J. Environ. Res. Public Health 16(12): 2123
10.3390/ijerph16122123‍ ‍
Barlow, C.A., M.J. Kemp, C.A. Boyd, and K.A.H. Parr.
2019 J N Engl Water Work Assoc 133(4): 243-255
Burns, A. M., C. A. Barlow, A. M. Banducci, K. M. Unice, and J. Sahmel.
2019 Risk Anal 39 (12):2604-7
10.1111/risa.13401‍ ‍
Burns, A. M., C.A. Barlow, A.M. Banducci, K.M. Unice, and J. Sahmel.
2019 Risk Anal 39(10): 2272-2294
10.1111/risa.13312‍ ‍
Scott, P.K., M.M. Abramson, J.L. Bare, and C.A. Barlow.
2019 EM-Mag Env Mgrs. January 2019
Mishra, R., D.G. Foster, J.H. Finigan, and J.A. Kern.
2019 Biochem Biophys Res Commun 513(4): 794-799
10.1016/j.bbrc.2019.04.070‍ ‍
Leach, S.M., J. Finigan, V.T. Vasu, R. Mishra, M. Ghosh, D. Foster, R. Mason, B. Kosmider, E. Farias-Hesson, and J.A. Kern.
2019 Am J Respir Cell Mol Biol 61(4): 481-491
10.1165/rcmb.2018-0283OC‍ ‍
Afzali, M.F., K.A. Popichak, L.H. Burton, A.L. Klochak, W.J. Wilson, S. Safe, R.B. Tjalkens, and M.E. Legare.
2018. Mol Immunol 101:4 6-54.
doi: 10.1016/j.molimm.2018.05.024.
McMullin T., A. Bamber, D. Bon, D. Vigil, and M. VanDyke.
2018 Int J Environ Res. Public Health 15(7): 1500
10.3390/ijerph15071500‍ ‍
Abramson, M.M., J.L. Bare, C.A. Barlow, and P.K. Scott.
2018. Paper #410832. Proceedings of Air and Waste Management Association's (AWMA) Annual Conference and Exhibition, June 25-28, 2018. Hartford, CT. 2018
Barlow, C.A., G.M. Marsh, S. Benson, and B.L. Finley.
2018. Toxicol Appl Pharmocol 361: 173.
10.1016/j.taap.2018.05.036‍ ‍
Drechsel, D.A., C.A. Barlow, J.L. Bare, N.F. Jacobs, and J.L. Henshaw.
2018 Reg Tox Pharm 92: 251-267
10.1016/j.yrtph.2017.12.005‍ ‍
Barlow, C.A., M. Grespin, and E.A. Best.
2017 Inhal Toxicol 29(12-14): 541-554
10.1080/08958378.2018.1435756‍ ‍
Barlow, C.A., J. Sahmel, D.J. Paustenbach, and J.L. Henshaw.
2017 Crit Rev Tox 47(4): 286-316
10.1080/10408444.2016.1258391‍ ‍
Sahmel, J., C.A. Barlow, S.H. Gaffney, H.J. Avens, A.K. Madl, J. Henshaw, K. Unice, D. Galbraith, G. De Rose, R.J. Lee, D. Van Orden, M. Sanchez, M. Zock, and D.J. Paustenbach.
2016 J Expo Sci Environ Epidemiol 26(1): 48-62
10.1038/jes.2015.15‍ ‍
Mishra R., D. Foster, V.T. Vasu, J.V. Thaikoottahil, B. Kosmider, H.W. Chu, R.P. Bowler, and J.H. Finigan.
2016 Am J Respir Cell Mol Biol 54(6): 853-864
10.1165/rcmb.2014-0437OC‍ ‍
Han K.J., D. Foster, E.W. Harhaj, M. Dzieciatkowska, K. Hansen, and C.W. Liu.
2016 Hum Mol Genet 25(7): 1392-1405
10.1093/hmg/ddw021‍ ‍
Sahmel, J., H.J. Avens, P.K. Scott, K. Unice, A. Burns, C.A. Barlow, A.K. Madl, J. Henshaw, and D.J. Paustenbach.
2015 Inhal Toxicol 27(14): 787-801
10.3109/08958378.2015.1110216‍ ‍
Sahmel, J., C.A. Barlow, B. Simmons, S.H. Gaffney, H.J. Avens, A.K. Madl, J. Henshaw, R.J. Lee, D. Van Orden, M. Sanchez, M. Zock, and D.J. Paustenbach.
2014 Risk Anal 34(8): 1448-68
10.1111/risa.12174‍ ‍
Barlow, C.A., L. Lievense, S. Gross, C.J. Ronk, and D.J. Paustenbach.
2013. Inhal Toxicol 25(9): 553-67.
10.3109/08958378.2013.807321‍ ‍
Li, W., R.S. Laishram, Z. Ji, C.A. Barlow, B. Tian, and R.A. Anderson.
2012 Mol Cell 45(1): 25-37
10.1016/j.molcel.2011.11.017‍ ‍
Finley, B.L., J.S. Pierce, A.D. Phelka, R.E. Adams, D.J. Paustenbach, K.A. Thuett, and C.A. Barlow.
2012 Crit Rev Toxicol 42(2): 119-46
10.3109/10408444.2011.636028‍ ‍
Han, K.J., D.G. Foster, N.Y. Zhang, K. Kanisha, M. Dzieciatkowska, R.A. Sclafani, K.C. Hansen, J. Peng, and C.W. Liu.
2012 J Biol Chem 287(52): 43741-43752
10.1074/jbc.M112.372318‍ ‍
Ball, K.A., A.W. Nelson, D.G. Foster, and R.O. Poyton.
2012 Biochem Biophys Res Commun 420(4): 727-732.
10.1016/j.bbrc.2012.03.050‍ ‍
Laishram, R.S., C.A. Barlow, and R.A. Anderson.
2011 Nucleic Acids Res 39(18): 7961-7973
10.1093/nar/gkr549‍ ‍
Barlow, C.A., R.S. Laishram, and R.A. Anderson.
2010 Trends Cell Biol 20: 25-35
10.1016/j.tcb.2009.09.009‍ ‍
Mellman, D.L., M.L. Gonzales, C. Song, C.A. Barlow, P. Wang, C. Kendziorski, and R.A. Anderson.
2008 Nature 451: 1013-1017
10.1038/nature06666‍ ‍
Barlow, C.A., K. Kitiphongspattana, N. Siddiqui, A. Shukla, M.W. Roe, B.T. Mossman, and K.M. Lounsbury.
2008 Apoptosis 13: 681-692
10.1007/s10495-008-0203-z‍ ‍
Barlow, C.A., T.F. Barrett, A. Shukla, B.T. Mossman, and K.M. Lounsbury.
2007 Am J Physiol Lung Cell Mol Physiol 292: L1361-369
10.1152/ajplung.00279.2006‍ ‍
Barlow, C.A., A. Shukla, B.T. Mossman, and K.M. Lounsbury.
2006 Am J Respir Cell Mol Biol 34: 7-14
10.1165/rcmb.2005-0153OC‍ ‍
Pulver-Kaste, R.A., C.A. Barlow, J. Bond, A. Watson, P.L. Penar, B. Tranmer, and K.M. Lounsbury.
2006 Am J Physiol Heart Circ Physiol 291: H97-105
10.1152/ajpheart.00753.2005‍ ‍
Barlow, C.A., P. Rose, R.A. Pulver-Kaste, and K.M. Lounsbury.
2006 J Physiol 570: 59-64
10.1113/jphysiol.2005.098426‍ ‍
DeMali, K.A., C.A. Barlow, and K. Burridge.
2002 J Cell Biol 159: 881-891
10.1083/jcb.200206043‍ ‍

SCIENTIFIC PUBLICATIONS

Assessing systemic absorption and estrogenic potential of methylparaben and propylparaben in consumer use

Cellular defense mechanisms against asbestos fibers

Evaluating health impacts of exposure to PFAS mixtures: a systematic review of epidemiological studies using mixture methods

Asbestos fiber length and its relation to disease risk

Conditional BCL-2 Expression in Fibroblasts Promotes Persistent Pulmonary Fibrosis which is Reversible by Therapeutic BCL-2 Inhibition.

Pulmonary fibroblast subsets demonstrate differentially enriched signaling pathways during fibrosis resolution and repair.

Modulation of inflammatory pathways by omega-3 fatty acids in knee joint health for the management of post-traumatic osteoarthritis: a review.

Assessing systemic absorption and estrogenic potential of methylparaben and propylparaben in consumer use.

Anionic citrate-based 3D-printed scaffolds for tunable and sustained orthobiologic delivery to enhance tissue regeneration.

Structural, functional, and proteomic based sex differences in murine post-traumatic osteoarthritis development following mechanical anterior cruciate ligament injury.

Regeneration of biomechanically functional tendon tissue following injection of uncultured, autologous, adipose-derived regenerative cells into partial Achilles tendon defects in rabbits.

Cellular defense mechanisms against asbestos fibers.

Insight and benefits from vaccine clinical trials with adaptive designs: A scoping review.

Digital media use and mental health in adolescents.

Evaluating health impacts of exposure to PFAS mixtures: a systematic review of epidemiological studies using mixture methods.

Immunization against nucleus pulposus antigens to accelerate degenerative disc disease in a rabbit model.

Removal of the infrapatellar fat pad and associated synovium benefits female guinea pigs in the Dunkin Hartley model of idiopathic osteoarthritis.

Inhibition of antiapoptotic BCL-2 proteins with ABT-263 induces fibroblast apoptosis, reversing persistent pulmonary fibrosis.

Systemic iron reduction via an iron deficient diet decreases the severity of knee cartilage lesions in the Dunkin-Hartley guinea pig model of osteoarthritis.

Systemic administration of a pharmacologic iron chelator reduces cartilage lesion development in the Dunkin-Hartley model of primary osteoarthritis.

Saracatinib, a selective Src Kinase Inhibitor, blocks fibrotic responses in preclinical models of pulmonary fibrosis.

Age- and sex- associated differences in hematology and biochemistry parameters of Dunkin Hartley guinea pigs (Cavia porcellus).

Heat efficiently inactivates coronaviruses inside vehicles.

A practical PPE decontamination method using warm air and ambient humidity.

A pilot study to characterize hand-to-mouth transfer efficiency of organophosphate flame retardants identified in infant products.

PTPα Is a regulator of fibroproliferation during ARDS.

Influenza virus infection increases ACE2 expression and shedding in human small airway epithelial cells.

Role of mTOR as an essential kinase in SCLC.

Systemic iron overload exacerbates osteoarthritis in the strain 13 guinea pig.

A systematic review of the epidemiologic literature assessing health outcomes in populations living near oil and gas operations: study quality and future recommendations.

PFAS Toxicology – the science behind the variation in drinking water standards.

2019. Response to letter to the editor.

Potential airborne asbestos exposure and risk associated with the historical use of cosmetic talcum powder products.

Air dispersion modeling for historical community exposure reconstruction: An evaluation of the approach and its uncertainties.

Interleukin-6 is required for Neuregulin-1 induced HER2 signaling in lung epithelium.

The kinome of human alveolar type II and basal cells, and its reprogramming in lung cancer.

A novel diindolylmethane analog, 1,1-bis(3’-indolyl)-1-(p-chlorophenyl) methane, inhibits the tumor necrosis factor-induced inflammatory response in primary murine synovial fibroblasts through a Nurr1-dependent mechanism.

Exposures and health risks from volatile organic compounds in communities located near oil and gas exploration and production activities in Colorado (U.S.A.).

Evaluation of the uncertainties associated with the use of air dispersion modeling to estimate historical community exposure from manufacturers of asbestos-containing products.

The mineralogy and epidemiology of cosmetic talc.

Historical evolution of regulatory standards for occupational exposures to industrial talc.

Asbestos fiber length and its relation to disease risk.

History of knowledge and evolution of occupational health and regulatory aspects of asbestos.

Airborne asbestos take-home exposures during handling of chrysotile-contaminated clothing following simulated full shift workplace exposures.

Cigarette smoke induces human epidermal receptor 2-dependent changes to epithelial permeability.

Monoubiquitination of survival motor neuron regulates its cellular localization and Cajal body integrity.

Measured removal rates of chrysotile asbestos fibers from air and comparison with theoretical estimates based on gravitational settling and dilution ventilation.

Evaluation of take-home exposure and risk associated with the handling of clothing contaminated with chrysotile asbestos.

The role of genotoxicity in asbestos-induced mesothelioma: an explanation for the differences in carcinogenic potential among fiber types.

Star-PAP control of BIK expression and apoptosis is regulated by nuclear PIPKIα and PKCδ signaling.

Evaluation of tremolite asbestos exposures associated with the use of commercial products.

Ubiquitin-specific protease 9x deubiquitinates and stabilizes the spinal muscular atrophy protein-survival motor neuron.

Nitric oxide produced by cytochrome c oxidase helps stabilize HIF-1α in hypoxic mammalian cells.

CKI isoforms (α and ε) regulate Star-PAP target messages by controlling Star-PAP poly(A) polymerase activity and phosphoinositide stimulation.

Nuclear phosphoinositides: A signaling enigma wrapped in a compartmental conundrum.

A PtdIns4,5P2-regulated nuclear poly(A) polymerase controls expression of select mRNAs.

Protein kinase A-mediated CREB phosphorylation is an oxidant-induced survival pathway in lung epithelial cells.

Asbestos-mediated CREB phosphorylation is regulated by PKA and ERK1/2 through an oxidant-independent process.

Oxidant-mediated CREB activation: Calcium regulation and role in apoptosis of lung epithelial cells.

Ca2+ source-dependent transcription of CRE-containing genes in vascular smooth muscle.

Excitation-transcription coupling in smooth muscle.

Recruitment of the Arp 2/3 complex to vinculin: Coupling membrane protrusion to matrix adhesion.